GeneTex

  • Country / Location Selection

United States (US)

Desmoglein 1 blocking peptide

Cat. No. GTX88319-PEP

Species

 Human
Package
100 μg ($239)

APPLICATION

Product Note

The peptide was used in the production of GTX88319.

PROPERTIES

Form

Lyophilized powder

Buffer

Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O.

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Region/Sequence

C-YTTSDTLKPSVHVHD

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Desmoglein 1 , Cdhf4 , Dg1 , Dsg , Epkhe , Epkhia , Ppks1 , Sppk1 , Dsg1

Background

This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. [provided by RefSeq, Feb 2015]

Research Area

REFERENCE

There are currently no references for Desmoglein 1 blocking peptide (GTX88319-PEP). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for Desmoglein 1 blocking peptide (GTX88319-PEP). Be the first to share your experience with this product.
Submit a Review
Package List Price ($)
$ 239